An Artificial Intelligence (AI) Tool Enhancing Brain Tumor Treatment
An artificial intelligence (AI) tool has emerged to assist doctors in combating aggressive brain tumors. It aids in identifying crucial characteristics that provide guidance during surgery.
The Cryosection Histopathology Assessment and Review Machine (Charm)
The Cryosection Histopathology Assessment and Review Machine (Charm) is an advanced tool that efficiently analyzes images to identify the genetic profile of gliomas, a type of aggressive brain tumor. Currently, this process takes days or weeks. Kun-Hsing Yu, the senior author of a July 7 report in Med, explained that surgeons rely on detailed diagnoses to guide their operations.
Swift Predictions and Time-Saving Benefits
Although the tool’s accuracy cannot match current genetic tests, it can swiftly predict a tumor’s profile. This quick analysis enables doctors to proceed with appropriate treatment without needing to schedule and perform additional surgeries, saving valuable time, explained Yu.
Precise Assessment and Elimination of Wait Times
In addition, Charm can distinguish between malignant and benign tumor cells and determine the tumor’s grade, indicating its level of aggressiveness. These are assessments that human pathologists typically make during surgery. However, according to Yu, Charm could eliminate the need for a 10-to-15-minute wait or the presence of a pathologist on standby during the operation.
Glioma and Glioblastoma: A Grave Threat
Glioma — particularly the aggressive subtype known as glioblastoma — poses a significant threat, with untreated cases leading to death in less than six months. Tragically, only 17% of individuals diagnosed with glioblastoma survive beyond the second year, according to the American Association of Neurological Surgeons.
Superior Performance of Charm
Yu and his team trained a machine-learning algorithm using images of brain surgery samples and validating its accuracy against patient diagnoses. Charm performed better in identifying tumor genetic profiles than other AI systems.
Streamlining Decision-Making and Time-Consuming Processes
When making critical decisions about the extent of tissue removal and the potential use of drug-coated wafers in treating glioma tumors, surgeons heavily rely on the tumor’s genetic profile. Unfortunately, obtaining this information is a time-consuming process at present.
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